men who drink at least six or more cups of coffee a day may be cutting their risk of prostate cancer advanced of 60 per cent, suggests new research.
This is the first study important research specifically on the relationship between coffee and cancer of the prostate metastatic, researcher Kathryn senior, Wilson said. "It is an interesting finding, because there are not many of modifiable risk factors for prostate cancer."
A definite causal link is still far from proven, experts say just how coffee may help thwart prostate cancer is not clear.
"There is many compounds in coffee have different biological effects." It is an important source of antioxidants and may have anticancer effects, said Wilson, research in epidemiology at the Harvard School of Public Health, Boston. "Also, coffee appears to have effects on insulin and has been associated with a lower risk of diabetes type 2.". In addition, the insulin is supposed to play a role in many types of cancers, including prostate cancer. ?
Composed of coffee also have an impact on levels of sex hormones, according to the study of.
But at the present time, the point of finding only an association between a love of "java" and a better santée of the prostate. A study more is needed to confirm the results and if a biological explanation for the phenomenon exists, said Wilson.
The bottom line, she said: "it is probably too early to tell someone that [he or she] should go outside and start drinking coffee just because of this study.".
The report was published in the online edition of the journal of the National Cancer Institute on May 17.
Prostate cancer is the most frequently diagnosed cancer and the second leading cause of cancer death in men in the United States. In the United States, it affects one in six men in their lives. More than 2 million Americans and 16 million men around the world are the survivors of prostate cancer, say researchers.
The study, the Wilson team collected data on nearly 48,000 men who took part in the health professionals follow-up study and their follow up to 2008. Every four years since 1986 these men reported on how much coffee that they drank.
The researchers then calculated the risk of prostate cancer to the amount of coffee drunk. During the period of the study, they have identified 5035 case of prostate cancer, of which 642 were fatal cases in which the cancer was metastatic, which means that it had spread beyond the original site.
The Harvard team has found that drinking six or more cups of coffee per day was associated with a nearly 20% less risk of developing cancer of the prostate, with those who do step drink coffee.
In addition, the chances of developing the most lethal and advanced prostate cancer has decreased by 60%, compared with men who have refrained from coffee - a statistically significant parent and "substantially lower" risk, according to researchers.
Even men who drank less coffee - one to three cups per day - had a 30 percent lower risk of developing cancer of the prostate lethal, and risk reduction have been observed if the men drank caffeinated coffee decaffeinatedWilson group added.
After taking into account other lifestyle factors, such as age, smoking, obesity and exercise, the decline in the relative risk of prostate cancer remains, they said.
"This adds to the evidence of a variety of coffee diseases does not appear to be harmful," said Wilson. "It has been demonstrated quite regularly, to be associated with a lower risk of Parkinson's disease, type 2 diabetes and cancer of the liver." This is an another potential more coffee.
The study was limited by the prevalence and the absence of data on the consumption of coffee of previous periods of life among men, the researchers noted.
The finding comes on the heels of a study published last week which found that women who drank five or more cups of coffee per day has seen a significant decrease in their risk for a particularly aggressive form of breast tumours. The Swedish study, a team at the Karolinska Institute in Stockholm, was published in Breast Cancer Research.
Commenting on the results of the Harvard team, Eric Jacobs, strategic Director of Pharmacoepidemiology at the American Cancer Society, it calls a large, well designed study. But he stressed that, until now, it remains the only study to show such a link.
"It is premature to conclude that drinking coffee may help prevent fatal prostate cancer," he said. "We do, however, know that smoking and obesity are associated with a higher risk of prostate cancer fatal, and the death of many other diseases." "It is fine enjoy a nice cup of coffee, but avoiding smoking and maintaining a healthy weight are among the safest to stay in good health means".
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