many studies have attempted to link specific behaviors and health conditions at the onset of Alzheimer's disease, but scientists still cannot say with certainty that anything do you or not do prevent brain disorder, according to a review of the U.S. of recent research.
The National Institutes of Health of the United States convened a Conference in the spring last to analyse the 18 studies of potential risks, such as poor eating habits, a chronic disease factors, smoking or small exercise and the development of Alzheimer's disease.
"Although we are not dismissing the potential role or important that these major risk factors may play in the development of Alzheimer's disease, at this time with what we have currently, we cannot confirm the associations of any risk""," says senior study author Dr. Martha l. Daviglus, Professor of preventive medicine and medicine at Northwestern University Feinberg School of Medicine in Chicago.
"If we need to do research, if we want to have the evidence in hand,", she added.
The study, which summarizes the results of the NIH Conference, is published in online may 9 and printing September issue of the Archives of Neurology.
For the moment, age is the main factor of risk known for Alzheimer's disease, the study noted. A variant of gene is also associated with an increased risk, he said.
An approximately 5.3 million Americans struggling with Alzheimer's disease, a planned figure that aging population of Baby-Boomer of the country, said the authors. The disease is responsible for between 60 and 80% of cases of dementia.
"What we are talking about here is something that will affect many Americans in the years to come," said an expert, Catherine Roe, instructor in neurology at the medical school of Washington University in St. Louis. "In fact, it will be an explosion over the next 50 years, because everyone lives in General, most" she said.
The studies included in the analysis of the NIH Research conducted between 1984 and 2009 in English. The participants were at least 50 years old and living in developed countries.
Some of the studies addressed food influences, such as the intake of folic acid, Mediterranean diet and nutritional supplements. Others find a link between the health problems, such as diabetes or high cholesterol and Alzheimer's disease. Others still explored the consumption of alcohol and physical activity levels and the risk of Alzheimer's disease.
The NIH team found that, overall, the studies has been "compromised by methodological limitations" that restrict the ability to establish a strong association between any particular health or usual behavioral condition and Alzheimer's disease.
The authors noted that these limitations result from the use of poor diagnostic criteria, low knowledge of the inner workings of Alzheimer's disease itself, or the lack of reliability of the State of physical and mental health reported the patient.
Yet, despite determining that the current quality of evidence is "insufficient" to draw cause and effect links, Daviglus and colleagues noted that the public should still focus on the ways of life that avoid behaviours already linked to other chronic diseases.
"People should follow a healthy lifestyle, which includes exercise, not control blood pressure, smoking, not become excess weight or trying to sleep properly," said Daviglus.
"And, of course, our recommendation is that it is very important that we ensure that, in the future, more well-designed comparative studies be conducted so that we can get better quality outcomes that can confirm associations, when they existententre the risk factors which have a large proportion of the population and the onset of Alzheimer's disease.""," she added.
ROE has agreed that "quality additional research is needed", but added that, "I don't think it's worse than in any other area of research." It is a difficult and stimulating work. And it costs lots of money at a time when there a crisis of funding science. ?
However, a sense of urgency should prevail, said Roe. "Now Baby Boomers are hitting the age where Alzheimer's disease comes into play," she noted. "And it will take a huge loss of life and economic toll, if we do find a way to treat or slow down." Therefore it is very important that we do more and better. ?
No comments:
Post a Comment