A small study of women with cancer suggests that those who have already undergone surgery to receive breast implants not with no prognosis poorer than those without implants, despite the fact that mammograms were less precise pick up anomalies in this group of women.
Women who had breast implants were more likely to have tumors that can be detected by touch alone and were also more likely to have cancer that has spread in lymph nodes, but the rate of survival between the two groups in the study was similarresearchers have discovered.
"We found that women in the Group augmented had palpable tumors and were more likely to have nodes lymph positive disease," said study author Dr. Jessica a. Rayhanabad, a member of the division of surgery of the breast at Keck School of Medicine the USC in Los Angeles. "However, these conclusions are not translated into a significant difference in survival rates between the two groups."
But researchers have recognized that small sample size can biased that the rate of survival. Women whose cancer has invaded the lymph nodes generally have a poorer prognosis for survival, they noted, given that the tumor cells are then able to move by the bloodstream to other tissues and sites through the body.
The study, by researchers at the University of Southern California, is scheduled to be presented Friday at the annual meeting of the American Society of Breast Surgeons in Washington, D.C. Because of its size and because it has not yet been published in a peer review, the findings should be considered preliminary.
"It is commonly accepted that [a breast implant] impairs our ability to diagnose breast cancer and women increased have therefore a worse prognosis should they develop breast cancer," wrote the authors.
For the study, researchers reviewed records of 5,005 women, who had been treated for cancer of the breast in 15 years to determine whether patients with breast implants have been diagnosed more advanced disease and had thus a poorer prognosis. (In the medical language, the term breast implant is "augmentation mammoplasty.")
In the study, a total of 195 women had previously undergone breast augmentation and 121 had a mammogram before their diagnosis. The test showed no abnormal existing in 36 per cent of these cases, compared to a rate of false negatives from 15% in the general population.
However, researchers have found no difference in the size of the tumor, recurrence rates or rates of survival between the two groups.
Another surgeon of breast not involved in the research said that within 15 years of the study is an important limitation, because it suggests that the majority of patients probably did not undergo digital mammograms, which became much more widely used in since three or four years.
"Digital x-rays really made a big difference in terms of accuracy, because they can enter right through,", said Dr. Alexander j. Swistel, Chief of breast surgery at New York-Presbyterian Hospital/Weill Cornell Medical Center in New York.
Researchers have also noted that MRI can be an important tool for patients with implants, but Rayhanabad warned: "I'd make general recommendations for MRI screening on all women who have had breast augmentation.". It really depends on our ability to evaluate the chest on mammography. Get an MRI screening in an augmented woman should be at the discretion of the imaging of the chest and the surgeon.
According to the American Society of plastic surgeons, about winegrapes women undergo breast augmentation surgery last year, which is an increase of 39% from the year 2000.
"There is a level of comfort around implants I've ever seen, and it is for women of all ages," notes Swistel. "We now see young women who get implants in high school graduation gifts."
That comfort level may be unfounded, since the researchers noted that the study did not exclude the possibility of results in women with breast implants who develop breast cancer.
"One of the limitations of our study is the size of the small sample of women increased," said Rayhanabad. "We know that patients ganglion lymphatic-positive, on the whole, are more likely to have the poorest survival." "And it can therefore that the sample size may contribute to the lack of difference between the two groups, survival rates."
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