Friday, May 27, 2011

Sedentary jobs, helping the obesity epidemic Drive

 as Americans sit - literally - in more sedentary jobs, they're packing on the pounds, and it is this inertia which is a major contributor to the obesity epidemic, new research suggests.


Look at the computer for hours rather than hoeing the fields means that us are 120 to 140 burning less calories per day than they were 50 years ago.


Therefore promote any type of physical activity should be more important in this war the weight, according to a study in the Edition online may 25 in the journal PLoS ONE.


"It is calories in and calories out, and we're more calories in that we take, said Dr. Robert Graham, a primary care physician at Lenox Hill Hospital in New York."


Led an inclination towards calories in two-thirds of American adults are now overweight or obese.


Although dietary habits and exercise have been studied to the obesity epidemic, these researchers, from Biomedical Research Centre Pennington in Baton Rouge, Louisiana), stated that a large part of the responsibility for the extra weight was put on the caloric intake.


This is because the amount of recreational physical activity has not really changed over the years.


But what physical requirements of work, where so many people spend most of their days?


These researchers cross-referenced U.S. Bureau of Labor Statistics on the prevalence of different jobs with a large national database which includes information on body weight.


Fifty years ago, about half of private-industry jobs involved United States a kind of physical activity, things such as agriculture, mining, construction and manufacturing. Today, this number is less than 20%, with the dominance of jobs in the retail, education and business sale.


The authors estimate that less than 100 calories out each day would lead to weight gain in what the U.S. population has seen since the 1960s.


However, if Americans were following federal guidelines for physical activity (150 minutes per week of moderate intensity exercise or 75 minutes of more vigorous activity), these additional calories would have been levelled.


Only one in four Americans made the recommended exercise level, the authors reported.


"We need to encourage physical activity most, particularly given that us sit more during the day that we has 100 years," says Keri Gans, a spokesman for the American Dietetic Association and the author of the diet of Small Change.


"The requirements of daily life are in competition with exercise," said Graham. "We have just in time for it to do."


Gans recommends that people move to work even if they have what amounts to an employment office. That could take the stairs when you can walk on the counter of a co-travailleur when you can and taking a walk at lunch. And if your company happens to have a gym or exercise program, by all means, you will participate.

Oil of fish during pregnancy may not stimulate the vision of babies

NEW YORK - moms who take fish oil supplements may be not much done to sharpen the vision of their baby, a new study suggests.


The fly of some previous research findings that suggested Docosahexaenoic acid (DHA), found in fish oil, improves vision in premature infants who receive supplements in their first months of life.


DHA is an omega-3 fatty acid involved in the brain and Visual development. Given that the substance crosses the placenta, primarily more later during the pregnancy, preterm Miss on a large part of their prenatal supply.


Therefore extra DHA after birth could help make up for this.


In the new study, Australian researchers looked at whether prenatal fish oil helps improve vision in infants born at term.


They have tested Visual acuity in 185 4 - month - olds whose mothers had been assigned at random to take rich in DHA fish oil capsules or placebo (capsules of vegetable oil) daily progestogen until delivery.


Overall, there was no benefit of DHA on the vision of newborns, the researchers report in the American Journal of Clinical Nutrition.


It is not clear why supplements have an impact, despite the benefits seen in premature infants given DHA after birth.


But one reason may be that preterm need the extra DHA, while babies born at term get all that they need for normal Visual development while still in the womb, according to Dr. Maria Makridesthe principal investigator of the study.


"I think that if women are better nourished and have a good scheme varied, then DHA supplementation during pregnancy to improve visual development for their unborn baby is not necessary," Makrides, women and children Health Research Institute of North AdelaideEn Australiatold Reuters Health in an e-mail.


Researchers are still studying if there could be other benefits to the development of infants. But studies have so far are mixed.


In a study published last year, the Makrides team found no evidence this oil of fish during pregnancy babies relaunched cognitive and language skills at the age of 18 months (see history of Reuters Health, October 19, 2010).


Makrides said that this and other studies are highlighting the fact that in term infants born to mothers well fed generally do well development delay - and it can be difficult to improve with DHA supplements.


There may be other benefits of fish during pregnancy oil. Some studies have suggested that it may reduce the risk of preterm birth, for example, but it is still on this issue.


In General, experts recommend that pregnant women strive to 200 milligrams of DHA per day. Certain prenatal vitamins now wear the fatty acid, which is also present in fish, especially the more fatty such as salmon, mackerel and tuna.


However, since the fish may be contaminated with mercury, doctors advise pregnant women to limit to two meals of fish per week. They should also choose fish have Omega-3, but which are likely to have low mercury levels, such as salmon, canned light tuna and shrimp.


Some fish - shark, swordfish, mackerel King and Tile - should be completely avoided during pregnancy because they may have high concentrations of mercury.


Makrides, stated that his team continues to follow children in this study to see if the oil of fish during pregnancy makes no cognitive difference and four language skills at the age.

As for the Visual development, fish oil has any benefit for infants born at term, it would be more evident in early life.

"At the end of childhood," Makrides said, "it would be much more difficult to find differences between groups, such as Visual development would be well advanced."



Bu the vulnerable: antipsychotics atypical among children and the elderly

 Pharmaceutical companies have recently paid out the largest legal settlements in U.S. history - including the largest criminal fines ever imposed on corporations - for illegally marketing antipsychotic drugs. The payouts totaled more than $5 billion. But the worst costs of the drugs are being borne by the most vulnerable patients: children and teens in psychiatric hospitals, foster care and juvenile prisons, as well as elderly people in nursing homes. They are medicated for conditions for which the drugs haven't been proven safe or effective - in some cases, with death known as a known possible outcome.

The benefit for drug companies is cold profit. Antipsychotics bring in some $14 billion a year. So-called "atypical" or "second-generation" antipsychotics like Geodon, Zyprexa, Seroquel, Abilify and Risperdal rake in more money than any other class of medication on the market and, dollar for dollar, they are the biggest selling drugs in America. Although these medications are primarily approved to treat schizophrenia and bipolar disorder, which combined affect 3% of the population, in 2010 there were 56 million prescriptions filled for atypical antipsychotics.


In a presentation this week at an American Psychiatric Association meeting, Dr. John Goethe, director of the Burlingame Center for Psychiatric Research in Connecticut, reported that over the last 10 years, more than half of all children aged 5 to 12 in psychiatric hospitals were prescribed antipsychotics - and 95% of these prescriptions were for second-generation antipsychotics. Many of these children didn't have a condition for which the drugs have been shown to be helpful: 44% of youngsters with post-traumatic stress disorder (PTSD) and 45% of children with attention deficit hyperactivity disorder (ADHD) were treated with them.


Pharmacologically, the ADHD prescriptions make no sense: FDA-approved drugs for the condition raise levels of the neurotransmitter dopamine, while antipsychotics do they opposite, lowering them.


Geothe also noted another study that showed that the number of office visits by children and teens that included antipsychotic drug prescriptions rose 600% from 1993 to 2002. "The obvious second-generation bias is very apparent in these data, as is the irrational use of antipsychotics for indications such as PTSD and ADHD for which there is no controlled evidence whatsoever that these are safe or effective treatments," says Dr. Bruce Perry, senior fellow at the ChildTrauma Academy in Houston. (Full disclosure: Dr. Perry is my co-author on two books.)


The situation may be similar in state-run juvenile detention systems. Late last week, an exposé by the Palm Beach Post revealed that antipsychotics were among the top drugs purchased by the Florida Department of Juvenile Justice (DJJ), and were largely used in kids for reasons that were not approved by the government - for instance, sleeplessness or anxiety. The Post reported:

In 2007, for example, DJJ bought more than twice as much Seroquel as ibuprofen. Overall, in 24 months, the department bought 326,081 tablets of Seroquel, Abilify, Risperdal and other antipsychotic drugs for use in state-operated jails and homes for children.

That's enough to hand out 446 pills a day, seven days a week, for two years in a row, to kids in jails and programs that can hold no more than 2,300 boys and girls on a given day.

Among the psychiatrists hired by the state to evaluated incarcerated kids, about a third received drug company money, the Post reported. Those 17 psychiatrists wrote 54% of the prescriptions for antipsychotics; the 35 doctors who did not take such payments wrote the rest. In other words, one-third of doctors - all of whom were paid by drug companies - wrote more than half of all antipsychotic prescriptions for the state's locked-down youth.

The statistics on children in foster care are equally alarming. Youth in foster care are not only three times as likely to be medicated as comparable low-income youth on Medicaid, but more than half are treated with antipsychotics. It is not likely that all or even most of these children have a condition for which antipsychotics have been approved by the government to treat.


Among the problems with unnecessary use of antipsychotic medications is that they can cause serious, sometimes irreversible, damage. Atypical antipsychotics are associated with weight gain and may double users' risk of Type 2 diabetes. Recent research also suggests that they may shrink the brain and there is little data on how they affect brain development during the teen years, when the brain grows more than at any other time but infancy. Indeed, youth are more vulnerable than any other group to the drugs' worst side effects (excluding death).


"The majority of antipsychotic medication use in children and adolescents has not been limited to the few age groups or conditions for which there is credible evidence of efficacy and safety," says Perry. "There is no reason to expect irrational prescribers to change their bad habits."


He adds that many experts would argue that if doctors began prescribing antipsychotics "responsibly and cautiously" - that is, being mindful of the lack of efficacy data and the evidence of harm - the rate of prescriptions in children would drop by 90%.


Meanwhile, rates of prescriptions for patients at the other end of the lifespan are also out of control. In nursing homes, 14% of residents have been given at least one prescription for a second-generation antipsychotic, according to a government investigation. A full 88% of these prescriptions are given to people with dementia, despite the fact that these drugs may double the risk of death in these patients (there is a black box warning on the drug to this effect). The investigation estimated that $116 million Medicare dollars have been spent filling antipsychotic prescriptions that never should have been written.


So why are these drugs so widely prescribed? Aggressive drug company marketing is only one part of the story. A key reason they are overused in institutional settings is that they are sedating, making patients easier to manage. Secondly, unlike other sedative drugs, they are not associated with misuse (with the possible exception of Seroquel, which has fans among some addicts). In fact, most people resist taking antipsychotics, which is why overmedication is much more common in settings where people are locked-in and compliance can be forced.


(More on TIME.com: U.S. Aims to Reduce Overdose Deaths, But Will the New Plan Work?)


The second point - that these drugs are not considered addictive - by itself probably accounts for a big part of why drug companies have been able to get away with so much misleading marketing and the resultant overprescribing. Although prescribing of traditional sedatives like benzodiazepines (Valium, Xanax), which are vulnerable to misuse, is limited by their status as controlled substances, few people enjoy misusing antipsychotics (side effects like weight gain, pleasurelessness, movement disorders and low energy and motivation are not generally sought by recreational drug users), so they can be prescribed for unapproved uses like behavior control and sleep-inducement in children and the elderly.


In other words, addiction is basically seen as a worse side effect than death. The fact that the most vulnerable youth and elderly often cannot advocate for themselves has made it easier to sweep the problem under the rug.

Fortunately, there is at least one bright spot in this depressing picture. The main patent on Risperdal expired in 2007, and those for Zyprexa and Seroquel expire this year. Geodon's patent expires next year, while Abilify's comes up in 2015. When most drugs go off-patent, drug companies' marketing pressure - and profits - will subside, perhaps keeping children and the elderly safer from inappropriate medication.

NIH stops to the study of niacin to prevent crises cardiac

WASHINGTON - a drug that stimulates the good popular cholesterol not a go to prevent heart attack or stroke, leading authorities to abruptly stop an important study Thursday.


Disappointing results imply niacin super-strength, a type of vitamin b that many physicians prescribe already as a potential heart protection. Study failed mark the latest setback in the quest to exploit the good cholesterol against bad type.


"This sends a little to the drawing board", said Dr. Susan Shurin, cardiovascular Chief at the National Institutes of Health.


The wrong kind of cholesterol, called LDL, is the main source of artery clogs. Popular statin drugs, sold under such names as Zocor and Lipitor, generic shapes, are the pillars by lowering LDL. Yet many Statin users still have heart attacks, because LDL is not history.


Cholesterol HDL, the good kind, helps combat accumulation artery carrying fats in the liver to be disposed of. It is one of the reasons that people with too little HDL are also at risk of heart disease. If scientists are checking if giving HDL-stimulate statin drugs could provide cardiac patients added protection.


The latest study tested Abbott Laboratories' Niaspan, a form of niacin extended-release is a dose more than found in food supplements. The drug has been sold for years, and previous studies have shown that it increases levels of HDL. But nobody knew if that translates in heart attacks.


Researchers enrolled more than 3 400 Statin users to the United States and the Canada who had heart disease stable and controlled LDL, but was at risk due to low concentrations of HDL and too much a different bad fat triglyceride. They received Niaspan or a dummy pill to add to their daily medicine.


As expected, Niaspan users saw their rise of levels of HDL and their levels of drop of more than risky triglycerides people taking a statin alone. But the treatment of the combination does not reduce heart attacks, stroke, or the need for compensation artery as angioplasty procedures, said the NIH.


This conclusion "" unexpected and striking contrast with the results of previous tests, "said Dr. Jeffrey Probstfield, Washington University, who helped conduct the study."


But he led the NIH to stop the study 18 months in advance.


Adding the decision was a small increase of strokes in users high-dose niacin — 28 among those 1,718 given Niaspan, compared to 12 among the users of 1,696 placebo. The NIH said that it was not clear if this small difference was simply a coincidence. previous studies have shown no risk of stroke of niacin. In fact, some of the strokes occurred after Niaspan users stop taking this drug.


What is the message for cardiac patients?


Users Statin that have very low LDL levels, like those in this study have not need an additional prescription for niacin, said Dr. Robert Eckel, cardiologist of the University of Colorado and spokesperson for the American Heart Association who was not involved in the study.


But it is not clear if niacin would have no effect on people at high risk or those who do not yet have a diagnosis of heart disease, but take niacin as preventive, said study co-leader Dr. William Boden, of the University at Buffalo.


"We cannot generalize these findings... for patients that we investigate," he said.


Eckel said it is "really hard to envision exactly what will happen in offices of physicians" in coming weeks as they discuss the niacin with patients. The NIH has urged people not to stop high-dose niacin without consulting a physician.


Neither the conclusions stop hope that raise HDL finally will be panoramic, Eckel said. While two other drugs were not so, it closely monitors some much higher HDL-boosters, including a drug from Merck & Co., called anacetrapib, which are being developed.

Legislators run scared of reforming Medicare

WASHINGTON- a democratic victory in a reliable Republican district House of representatives this week has legislators cops to reform Medicare, greatly reducing the chances of a global agreement to reduce the deficit in the long term.


Rarely in recent years was a special election unique, off the coast of the year - such as in a district of the House Tuesday in the State of New York - raised these earthquakes of policies at the national level or have had these efforts to bring us federal debt under the control of the negative impact.


Democrat Kathy Hochul won a solidly Republican district after hammering his opponent to save a Republican plan in the House, to scale back Medicare costs. Medicare is a federal program which is the biggest single driver of deficit, but most voters want left intact.


Without a sincere effort to curb the growth of Medicare, which provides health insurance, to elderly and disabled US $ 47 million it will run short of money in 13 years.


Remained unchanged, Medicare, social security retirement program and the program of insurance of federal State of Medicaid for the poor would consume 100 percent of all tax revenues by 2047, according to the non-partisan Government Accountability Office.


Republicans recaptured control of the House in 2010 in part by Democrats accusing bar to slash Medicare and interfere with the doctor-patient relationship under health reform law signed year last by President Barack Obama. The Act is often derided by opponents as "obamacare."


Democrats believe that the political situation has been changed.


At issue is a Republican proposal put forward in April by House Budget Committee Chairman Paul Ryan would fundamentally reshape Medicare into an agreement in which seniors receive government benefits to help pay for private health insurance.


The impartiality that Congressional Budget Office estimated that the Ryan budget would eventually double Medicare small expenditure for the elderly.


Polls show that while voters want action to bring down the deficit - defined for $ 1.4 billion this year, overwhelmingly that they oppose any changes to Medicare.


Tim Pawlenty and Mitt Romney, regarded as the major candidates for the Republican presidential nomination in 2012, have backed away from Ryan plan.


Although the Senate Republicans appear to be maintained by Ryan plan in a vote Wednesday, some have conceded that their vote was the unity of the party more than real support to overhaul Medicare. The Senate under democratic control defeated the proposal by Ryan passed to the House by a vote of 57 to 40, with five Republican senators voting against it.


"ARTICLE OF FAITH".


Republican Senator Bob Corker said there was no Republicans of the Senate who considers an "article of faith".


A Republican strategist, speaking on condition of anonymity, said that Republicans would rather campaign the year next to the high unemployment rate that "tell voters why they want to dismantle Medicare.".


"The Republican budget is a political responsibility and toxic for the GOP," Democratic Senator Patty Murray said, referring to the nickname of Grand Old Party of Republicans. Competition of the House on Tuesday "remembered as a turning point in the next election."


With the Democrats having now every policy encourages not to address the costs of Medicare and wishing to avoid the problem of many Republicans, said analysts election on Tuesday was also a decisive moment - and non-positive - for the long-term deficit.


"It is amazing what can have a ripple effect, a special election", David Gergen, a political analyst and Adviser to four Presidents of the United States, told Reuters.

"The election of New York the makes more difficult to reach a global agreement on the reduction of the deficit - before the elections in 2012 and what happens after 2012 is therefore uncertain." This makes it more likely that they could kick the can on the road, in 2013 or 2014. ?

With the largest insurance and one of the fastest growing budget components, the important deficit reduction simply cannot be achieved without some savings in the programme.

Recent elections have shown what a politically explosive issue Medicare is - and the part that attempts to change the fact at his peril.

In 2010, Democrats accused Republicans of wanting to "death panels" for the elderly in their health care proposals. The benefits of the bitter struggle on the right lead healthcare helped helped new big Republican wins the legislative elections last November.

This week, a non-profit group Liberal, in an attack on the Ryan plan, has published an advertisement showing an old woman thrown a cliff of her wheelchair - an image that could be taken up by the Democrats, as the 2012 elections draw approach.

Republicans are the image of these efforts are "mediscare" tactical.

Ryan, speaking at a financial Summit in Washington said Obama and Democrats had decided of "shamelessly distort and demagogue Medicare,"and warned that without reform,"it went bankrupt and we will go in a debt crisis."

Former President Bill Clinton, who waited to be re-elected for a second term to address the reform social, warning the Democrats against the use of insurance for "political gains in the short term."

Now, freed from the political constraints of Office, Clinton flatly said fellow Democrats: "we have to deal with these things." You can't have healthcare devour the economy. ?










Lists of the side effects of the Prescription Meds continued growth: study (HealthDay)

(Thursday, May 26, HealthDay News) - lists of the side effects of prescription drugs on drug labels, packaging and advertisements have proliferated to an average of 70 by drug, a new study reports.

Warnings on side effects have been designed to inform physicians and consumers of the potential hazards, but this expansion may have had more to do with concerns over disputes rather than real health problemssay the authors of the study, which argue that the information could be presented much more effectively.

"Having a high number of side effects on the label of a drug should not suggest that the drug is dangerous." In fact, much of this labelling has less to do with toxicity real to protect manufacturers from possible prosecution, "principal investigator study author Dr. Jon Duke, Regenstrief Institute and Assistant Professor of medicine at the Indiana University School of Medicine"said in a press release from the University.

An analysis of more than 5,600 tags drugs and side effects more than 500 000 concluded that prescription drug labels include an average of 70 different adverse potentials - a number which jumps to 100 of the side effects of some commonly prescribed drugs.

Some drugs in the upper range listed even 525 reactions.

Duke pointed out that the large number of listed side effects could overburden physicians to browse this information to make informed decisions about medications for their patients.

For the study, published in issue 23 May of the Archives of Internal Medicine, researchers have compiled a list of prescriptions drug types who were most likely to have a high number of marked side-effects. These drugs include antidepressants, antiviral drugs and new treatments for restless legs syndrome and Parkinson's disease.

Despite the enormous amount of information found in the labelling of current drugs, Duke argued that data could be useful if presented properly.

"With the current technology, drug labels could be processed long static documents from dynamic resources capable of providing custom patient information." "These labels could take into account medical conditions of the individual patient and to highlight the side effects that may be particularly dangerous," he said.

"We cannot stop the growing wave of drug information, but we can do a better job of presenting effectively to health care providers," Duke found.

More information

The U.S. Food and Drug Administration provides additional information on side effects of drugs.

New drug extends survival for men with advanced prostate Cancer

for men with advanced hormone-resistant prostate cancer who have failed also chemotherapy, the new drug Zytiga (abiraterone acetate) with the steroid prednisone appears to boost survival, researchers report.


Based on current clinical trial data, Zytiga has been approved by the Food and Drug Administration in April. It works by inhibiting the production of the hormone male testosterone, that promotes the growth of cancer cells. In this regard, the drug mimics the hormone therapy.


Zytiga "extends overall survival in this patient population which had very limited treatment options after chemotherapy" researcher principal Dr. Fred Saad, Chief of Urology at the hospital Notre-Dame de Montréal, said at a press conference of Monday morning.


The men in the combination of drugs had a mean survival of 14.8 months, compared to 10.9 months for men taking placebo.


"Abiraterone represents an option of valuable treatment for patients with metastatic castration [hormone] - resistant of the prostate which had been previously treated with chemotherapy, very easy to manage, treatment-related toxicity in" Saad said.


The study was published in issue 26 May of the New England Journal of Medicine. The findings were also presented may 16 at the annual meeting of the American Urological Association, in Washington, D.C.


The study focused on the 1,195 men prostate cancer that has not responded to hormone therapy and that he had no prior chemotherapy. Researchers, hospitals of 147 in 13 countries, randomly men to take Zytiga more prednisone or placebo.


The combination of drugs was well tolerated and has given rise within fatigue, back pain and spinal compression taking men, compared to placebo, Saad said.


The most common side effects in people taking prednisone and Zytiga were lower white blood cell, a retention, rates of low potassium, abnormal liver function tests, blood pressure and heart problems, the researchers noted.


A one month supply 120 pills of Zytiga costs $ 5,000, said Kelly McLaughlin, a spokesman of Centocor Ortho Biotech Inc., manufacturer of the drug and a promoter of the study.


"This study tells us that there is a form of hormonal treatment, abiraterone, who works among people who had chemotherapy and hormonal treatment standard," said expert Dr. Anthony D'Amico of prostate cancer, head of the apparatus Genitourinary Oncology at Brigham and women's Hospital in Boston.


"It will provide people with the disease late with an opportunity for a prolonged survival that they had not before." "I can't say that it is a term of home because it is only a few months improved,", he added.


Aggressive prostate cancer may be able to make its own testosterone, cancer cells need to grow. "Zytiga blocks that", said D'Amico.


"This drug offers longer life and better quality of life in men with very advanced prostate cancer," said D'Amico. "There are studies now to see if this medication will improve the rate of healing in men with advanced, but not [metastatic cancer that has spread to other organs], prostate cancer,", he added.

Thursday, May 26, 2011

Prostate Cancer studies find advantage in daily acetaminophen and walks Brisk

POP a Tylenol and take a brisk walk for protection against prostate cancer? This is what the results of two new studies published this week suggested.


In the first study, published Monday in the journal Cancer Epidemiology, biomarkers and prevention, scientists have found that men who took a daily dose of acetaminophen (Tylenol) for five years had a 38% lower risk of developing cancer of the prostatecompared with men. In addition, daily acetaminophen has been associated with an of 51% reduced risk of developing an aggressive form of the disease. The men who took acetaminophen for less than five years saw no protective benefit.


Previous research has shown that taking aspirin or other drugs anti-inflammatory drugs (NSAIDs) every day can reduce the risk of prostate cancer. The authors believe that the same may be true of acetaminophen; While not an NSAID, it has anti-inflammatory properties.


For the study, researchers looked at data 78,485 men who participated in the longitudinal Cancer Prevention study II Nutrition cohort, answering questions on the use of food and pharmaceutical plan every two years from 1992. During the period of follow-up, there were 8,092 cases of prostate cancer - much less in the group who took acetaminophen daily for five years.


The second study, published Tuesday online research on Cancer, involved 1,455 men who had already been achieved in prostate cancer stage. Researchers at the University of California, San Francisco (UCSF) and Harvard School of Public Health, then the men from 2004 to 2009 and found that those who engaged in regular brisk walking after diagnosis were significantly less likely to see their progression of the disease.


Men who walked fast - at a rate of approximately 3 miles per hour or faster - at least three hours per week were 57% less likely to experience of the progression of the disease (including high levels of PSA)(, secondary treatment of bone metastases and prostate cancer-related deaths), compared with men who walked less and more slowly.


"The important point is the intensity of activity," Erin Richman, a postdoctoral fellow at UCSF, said in a statement. "The March must be rapid for men to experience an advantage."


Researchers have said that the effect of speed walking remains independent of age, diagnosis, type of treatment and characteristics of the disease. Average age of patients at diagnosis was 65. The findings are consistent with previous research, which suggests that physical activity can help reduce the risk of deaths from the disease in some cases of prostate cancer.


Why the association? Reports MedPage Today:

Richman and his colleagues have noted that brisk walking may reduce resistance to insulin, which reduces bioavailable,-1 (IGF1) insulin-like growth factor and increases adiponectin levels, which are all associated with the decrease in the risk of prostate cancer advanced or fatal in vitro and in vivo.

Another potential source of reduction is inflammation reduced due to low circulation of Interleukin-6, high levels of which "predicts risk of 73% increased to die of cancer of the prostate in men of normal weight."wrote the researchers.

Prostate cancer is the second leading cause of cancer death in men. According to the National Cancer Institute, men about 32,050 die of cancer of the prostate in 2010 and 217,000 new cases were diagnosed. More than 2.2 million of men to the United States with prostate cancer.

Study: 6.5% of adults active enough to work

ATLANTA - if you think that you do enough physical activity to work for you keep healthy, you are probably wrong.

Health researchers that only about 6.5 percent of American adults meet physical activity guidelines, while they work. And those that do are disproportionately Hispanic men with less than a high school diploma.

The national estimate - the first of its kind - was reported Thursday in a Centers for Disease Control and Prevention publication, morbidity and mortality Weekly Report. It is based on a national telephone survey 2007.

Somewhere between 45% and 65% of adults say they have enough outside of work to respond to the recommendations of the Government for physical activity, after previous studies.

Optimistic rock on Avastin in cancer of the ovary

ZURICH - Roche Holding AG, the world leader in Oncology medicines, struck an optimistic tone about the Outlook of its key Avastin drug approval in ovarian cancer prior to a meeting important industry next month.


Head of pharma group that Pascal Soriot told journalists Thursday he was confident Avastin will win European approval and it was also relatively optimistic for win U.S. drug support.


"In Europe... we are confident because generally in Europe you can get approval on the basis of data of good progression-free survival," Soriot said.


"In the United States, we still wait until the data are fully mature to see what the overall survival data are similar and get a good sense of the FDA response, but I must say that we have seen so far... we made relatively optimistic that we have a good chance at the United States.". Thus, "he says.


Application for Avastin, used to treat a range of tumours, has fallen over recent quarters after the drug was struck by the movements of the two sides of the Atlantic health authorities to limit its use in breast cancer.


Roche now rely on the use of the vendor of billions of dollars to treat cancer of the ovary to stimulate growth future sales and intends to submit for the approval of the United States, later this year once he gave overall survival. She has already filed for approval in Europe.


"We will demonstrate that avastin has an essential role to play in cancer of the ovary," Soriot said before the Conference of the American Society of Clinical Oncology (ASCO) earlier this month next to Chicago.


"Overall superb new data showing our pipeline progresses." We hope that the shift in the perception of Avastin, "Soriot said, referring also data on lung and skin cancer drugs that will be presented at the ASCO."


OPPORTUNITY BUSINESS


Roche will present data impact on MetMAb of lung cancer and was to produce this treatment for approval in 2014, Soriot said, adding that Roche also sought to develop the drug in other diseases such as breast cancer.


Doctors and investors will be also eyes studies on vemurafenib, a drug to treat the deadliest form of skin cancer.


Soriot, said the business opportunity of vemurafenib has been limited to the skin cancer metastatic because the smaller number of patients in this parameter, but there is more potential sales if it were to be developed in the adjuvant.


The Group has yet to decide on setting prices of treatment and has therefore not yet a peak estimate sales for it.


Drug of rock, which develops with private holding Plexxikon and ipilimumab, an experimental drug developed by the US group Bristol - Myers Squibb, are giving hope to patients who already had a few treatment options.


Soriot said there was a place for both agents and it looks vemurafenib as the first line of treatment in patients who are positive BRAF.


"Ipilimumab is a different officer." It is a compound based on the immune system to treat cancer. It is a drug which can potentially be given to all patients, while vemurafenib can only be given to patients who are positive BRAF, which is approximately 50% of patients with cancer melanoma, "Soriot said."


"It is important to keep in mind that the percentage of patients who respond really well to ipilimumab is relatively limited." These patients have a strong response, but it is a small percentage, probably 10 per cent of the patients, who meet, "he says.

Spanish poet honors overlooked hero of the Warsaw Ghetto

MADRID - largest second poetry prize of the Spain was awarded this year to a volume honoring the heroines overlooked, including Irena Sendler, who saved 2,500 Jewish children by their smuggling of the Warsaw Ghetto.


Sendler has been nominated for the Nobel Prize for peace in 2007, a year before his death. She lost to former US Vice-President Al Gore and the Intergovernmental Panel on climate change.


"It is quite clear that it could have been truly worthy recipient of the award (Nobel Prize), no question, said Fatima Frutos, winner of the poetry Kutxa Ciudad de Irun 2011 Prize, ahead of an international field of 204"


"The visibility of women must be justified, those that have been considered secondary, who had no recognition but deserve that and much more."


Frutos also recalls Artemisia Gentileschi, a prominent painter of 17th century Italian and Spanish of the 19th century writer Carolina Coronado, which is struggling to achieve recognition in the fields then dominated by men.


Moreover, it honours, among others, Carl von Weizsaecker, a nuclear physicist of the 20th century, who would later become a philosopher.


"I start with the stories and build their lyricism and poetry, to assert their verse by verse," she said. "It is not only about giving visibility to invisible women, but also to the geniuses of the 20th century whose work has yet to shake up the consciences of the 21st century."


The volume of the recipient of the "Andromeda Encadenada" (encha?né Andromeda) takes its title from the Greek mythological Princess who was chained to a rock, but figure that Frutos sees as a source of inspiration rather than a victim.


It follows his 2009 volume "De Carne y hambre" (of flesh and hunger), which won the international prize of the erotic poetry of Ateneo Guipuzcoano.


"The myth allows me to discover other women as she who, in real life, through extreme, but nevertheless came through, if not euphoric, then at least optimistic and stronger,"Frutos say.""


"Andromeda" also adopts a perspective of pan-European topical with poems dedicated to the 18th century German philosopher Novalis or lyric poet of the 19th century studied.


"Now there are many reasons to defend European culture, the European ideal, the feeling that there is no European first or second class, but that we all in this together," she said.


Frutos main inspiration as a writer was Miguel Hernandez, a Spanish poet who died in prison in 1942, during the dictatorship of Francisco Franco.


"Hernandez were inoculated we poison blessed poetry so that we can grow without rancor but with force to advance social justice," said Frutos, who works as an agent of the equality of the local government.


The price of Irun is the second valuable most award for poetry in Spain and is open to all writers in Spanish. When she collects the award on May 28, Frutos devote to his grandmother, who took her reciting poems by Hernandez, she had learned by heart, because she cannot read or write.


"She wakes without rancor with poetry." She knew how hard-hearted me with as to hands and cover me with stanzas by great writers, "she said."


"I am a poet because of it." It must be said that an illiterate woman who lived in poverty also knew how to raise an international poet laureate. ?

Skin Cancer foes declared may 27 "Don't fry day" (HealthDay)

on Friday, the beginning of the end of week Memorial Day, is also "Don ' T fry day," once for skin safety experts remind Americans about the dangers of overexposure to the Sun.


Melanoma, the potentially deadly form of skin cancer is the most common cancer in young adults in the late twenties, according to the U.S. Environmental Protection Agency (EPA) and the National Council for the prevention of Skin Cancerwho have joined forces to offer advice to save lives on the caution in the Sun. The main cause of skin cancer: overexposure to harmful ultraviolet (UV).


"Many people still don't realize that exposure to the Sun without protection can lead to cancer of the skin and other health problems," said Gina McCarthy, agency Administrator assistant for the EPA Office of Air and radiation, in a press release. "Simple steps, such as using a sunscreen, wear sunglasses or a hat, can protect us and our families, while still enjoying the outdoors."


Skin cancer, the most common type of cancer in the United States, affects more than 2 million U.S. dollars - every year more breast cancer, prostate, lung and colon combined, said the EPA. Every hour, an American dies of cancer of the skin, the Agency noted.


Although the UV rays are dangerous year round, the risks are greatest in the summer months when people spend more time outdoors, McCarthy said.


To limit exposure to harmful UV rays, expert proposes to you:

Cover you. One of the most effective ways to reduce the exposure to the harmful rays of the Sun is to wear a shirt, hat and sunglasses and Sunscreen SPF 15 +. Find a shady place. It is best to stay out of direct light from the Sun during peak hours, from 10 h to 16 h being aware of the UV index. Get involved in outdoor activities, check the UV index to identify the time more risky for overexposure to the Sun.

Charity pulls smart stunt on pregnancy Bruni rumours (Reuters)

DEAUVILLE, France (Reuters) - at a glance of smart advertising, charity leader traded on rumours of possible pregnancy of Carla Bruni-Sarkozy to try to save the lives of babies in developing countries.

Before the Summit of the G8 rich countries who made the cut infant mortality a major theme in recent years, World Vision activists delivered a basket to the first lady of France with a kit of easily available in France delivery.

"What are simple products that any woman in Europe or North America can obtain at the pharmacy, but are inaccessible for many women in the developing world", Geraldine Ryerson-Cruz of the charity World Vision of Britain told Reuters.

Ryerson-Cruz said his charity is fighting to try to ensure that children around the world have the same chance of survival than the "first baby" French would have.

The French presidential palace has confirmed the pregnancy of Bruni, but the father of the President of the last week, Nicolas Sarkozy told a German newspaper that Bruni expects a child.

In the historic Villa Strassburger, World Vision activists delivered a basket with vitamins for pregnant women, a kit of safe delivery and hygiene supplies.

The basket was alcohol, surgical gloves, a razor blade for cutting the umbilical cord and sterilization baby care products.

Friday, Bruni will host first ladies of African nations participating in the Summit.

"As a French woman, Carla Bruni-Sarkozy is 150 times more likely to survive pregnancy and childbirth than a woman in the former French colony, Chad," Ryerson-Cruz said in an interview.

Ryerson-Cruz said that baby of the Bruni is also 52 times more likely to survive until the age of five as a baby with Chad, which has one of the worst years of child mortality in the world.

Sarkozy welcomed the leaders of the eight richest countries of the world to the posh seaside seaside Deauville Thursday and Friday. Several North Africa and sub-Saharan African heads of State will also attend the meeting.

Ryerson-Cruz said that estimates of Global Vision that mainly thanks to the initiatives of the g-8 in recent years the number of preventable deaths by the vaccination of children around the world declined approximately $ 4 million to approximately 8.1 million in 2010, 12.4 million in 1990.

Childhood treatments related to gastrointestinal problems

 children who are treated successfully for cancer are more at risk of developing severe mild gastrointestinal problems on the road, a new study concludes.


Researchers at the University of California, San Francisco analyzed the self-reported gastrointestinal (GI) problems of 14,358 patients surviving at least five years after the treatment of cancers such as lymphoma, leukemia, tumors of the brain or bone tumours.


More than 40 per cent have experienced some type of problem of IM - including ulcers, the disease of the esophagus, indigestion, polyps, chronic diarrhea, colitis, gallstones and jaundice - in two decades of their treatment, researchers have discovered.


In addition, people with cancer at a later age and who had to undergo a more rigorous treatment (chemotherapy, radiotherapy, surgery) were more likely to experience problems IM long term, according to the study of the may issue of Gastroenterology.


About one in 500 young adults in the United States is a survivor of childhood cancer, the study authors noted in a press release UCSF.


"While doctors continue to learn more about pediatric cancer and its treatment long term consequences, it is essential that we provide care of comprehensive follow-up that adequately addresses the complications can meet the cancer survivors.""," study lead author Dr. Robert Goldsby, specialist of pediatric cancer hospital for children of Benioff UCSF and Director of the UCSF Cancer of childhood survivors program, said in the press release.


"These are serious issues that can have a real impact on the quality of life of the person," added Goldsby.

Skeptical voters the Republican health insurance proposal

a Republican budget plan called for radical changes to Medicare took a Basinger in the US Senate, a day after voters in the State of New York expressed their disagreement in electing a Democrat.


On Wednesday the Senate under democratic control voted 57 to 40 against the budget proposal, which last month had passed the House of representatives Republican-controlled by a wide margin.


Although the outcome of the vote on Wednesday was determined in advance, five Republican Senators had joined their democratic colleagues in voting against the plan, which could radically alter Medicare, the popular program sponsored by the Government-health care for the elderly.


The vote followed a victory upset Tuesday for Democrat Kathy Hochul in a special election in the district of Congress New York 26th.


The election is triggered to occupy the normally safe Republican seat, left vacant by Chris Lee, who resigned after a gossip Web site published a photo featured bride Congressman responding to a personal ad.


Real drama of the election, was however, see how voters would react Republican proposals controversial to help trim the budget deficit growing transforming Medicare into a voucher program.


As the rest of his party, the Republican Jane Corwin campaigned in the district of New York State essentially rural, Western in support of health insurance reform.


Hochul campaigned against them - and won.


More immediate election reverberations were felt in Washington, where Democrats now see Republicans as deeply vulnerable on health insurance in the legislative elections and presidential 2012 next year.


Democratic Leader Harry Reid Senate called a vote on Wednesday to force Republicans to go to the folder for or against the Medicare budget plan.


Four centrist Republicans, Olympia Snowe and Susan Collins of Maine, Lisa Murkowski of Alaska and Scott Brown of Massachusetts, voted with the Democrats against the Republican regime.


Republican Rand Paul of Kentucky, Member of the ultraconservative ' tea party "and has also voted with the Democrats because he said that budget-cutting was not going far enough."


The budget plan calls cutting taxes for the wealthiest Americans and most importantly, a reduction in costs for Medicare and Medicaid, which provides health insurance for the poor citizens of the country. Opinion polls show that the two programs are extremely popular with voters.


Republicans were quick respond to voices, reprimand the Democrats to ignore the growing debt of the country's long-term impact.


"The President identified the problem more than a year ago, when he says that." almost any deficit long-term and debt we face relates Medicare and Medicaid,'"the Republican Senate leader Mitch McConnell, said.


"But Democrats in the Senate today showed that don't want to even talk about." They rejected every single proposal to deal with, "said McConnell.


"They are so focused on an election which is almost two years later that they may not see the crisis facing us", he added.


Democrats, on the other hand, contentedly on the protection of Medicare.

"The promise of Medicare is the following: If you work hard and contribute, America will ensure that you are protected retreat from difficulties to provide health care,"said Reid."."

"The Republican budget would break this promise", he added. "It would make life much more difficult and painful for America's seniors." It is as simple and as serious as that. ?

Scrambling to react to the vote on the budget of the Senate on Wednesday, the author of the plan original budget in the House, representative Paul Ryan, has published a video detailing what he said, were the "facts" on health insurance and its reforms.

Accusing Democrats of ignoring Medicare, funding issues, he said Republicans are trying to save the program, not kill it.

"Instead, to work with us, the leaders of the Democratic Party have chosen to play politics with the safety of the health of seniors in America," said Ryan.

Democrats, however, felt sure that they had found a powerful stick with which to beat the Republicans as they head after the first term of the Obama.

Rub salt in the wounds, Democrats released a "memo" Republicans in Congress, saying: "Revamping your"message"hide the facts." The Republican budget end Medicare as we know it... and the American people fooled by thinking otherwise. ?








Combo of Paxil, Pravachol may raise the sugar in the blood

 taken in combination, two drugs commonly prescribed antidepressant Paxil and the cholesterol-lowering Pravachol drugs seem increases significantly the blood glucose, a new study concludes.


The increase is more apparent - and for - in the diabetic whose blood sugar is already too high, the researchers noted.


"This interaction may affect up to 1 million Americans who would be on these two drugs and who get a bump in their blood glucose may be unnecessary," said researcher principal Dr. Russ Altman, Professor of biological, genetic engineering and medicine at Stanford University.


It is possible that the blood sugar spike triggered a diagnosis of diabetes type 2 patients, Altman said, "and we could avoid this diagnosis if they had not been on these drugs", he said. "This is speculative, but it is possible."


No single drug raises sugar in the blood and the researchers said they cannot yet explain the effect of the combination. Also, combinations of other antidepressants and cholesterol not stimulate glucose levels. "This is not what we would call a"class"effect", Altman explained.


Paxil (paroxetine) is in a class of drugs known as inhibitors of the reuptake of serotonin (SSRIS) and Pravachol (Pravastatin) belongs to a group of drugs called statins. "We looked at all the other pairs of SSRIS and Statins and there were a couple who has shown a small bump in glucose, but there is nothing to do with the humpback seen Paxil and Pravachol," Altman said.


For the study, published online may 25 in clinical and therapeutic Pharmacology, researchers have used a technique called data mining, analysis of large databases in the hope of finding information which, although not immediately obviousis gleaned by combining the data in a new way.


In this case, team Altman used the data from the U.S. Food and Drug Administration Adverse Event Reporting System, more data from the universities of Harvard, Stanford and Vanderbilt to identify the associations would not apparent doctors dealing with individual patients.


Using this method, researchers have identified 135 non-diabetic patients taking both drugs whose blood sugar increased of 19 milligrams per deciliter after the start of treatment. They have also identified 104 diabetic whose blood sugar increased an average of 48 mg/dl while taking the two drugs.


With levels of sugar in the blood of 126 mg/dl or two tests are considered diabetic. Levels of 100 mg/dl to 125 mg/dl are considered prédiabétiques.


By extrapolating these results to the whole of the population of the United States, the Altman team believes that of 33 million people taking Paxil or Pravachol, 500 000 to 1 million hold together.


To verify whether their conclusions were simply associations which could be explained by other factors, researchers have experimented with drugs in mice.


The mice were exposed to two drugs after receiving a diet rich in fat, high calorie to pre-diabetic. No single drug has increased sugar in the blood, together they have increased sugar in the blood of about 128 mg/dl to 193 mg/dl, the researchers found.


"It was just like humans in our data base, said Altman." So, this seems to be a real biological effect. "This could give us an overview of the mechanisms of diabetes."


Altman warns that people taking this drug combination should not respond.


He has said "people on an antidepressant should not mess with because depression is a very serious illness". It would be reasonable to see a doctor and see if your blood glucose have been difficult to control, he said. He said "if it was, then I think the thing to change would be the Statin,".


Dr. Ronald b. Goldberg, Professor of medicine at the Institute for research of diabetes at the University of Miami Miller School of Medicine, said that it was "" an interesting conclusion and could be clinically important. ""


"People with diabetes have an increased risk of depression." they are all recommended to be on Statins, "said Goldberg. "Then, it can worsen glycemic control in diabetic people."

But Goldberg thinks that it is too early to change clinical practice based on this study only. "This must be confirmed in a clinical trial," he said.



Commitment capacity can begin early childhood (HealthDay)

the ability of men and women of power staying and a high level of commitment in their relationships back to their childhood and adolescence, a new study concludes.


78 Persons aged 20 or 21 and their heterosexual partners on their level of commitment to their relationship, the researchers asked.


Researchers have already given on participants when they were between the ages of 16 and 2, including how loving and attentive, their mothers were while they were for toddlers, and how they dealt with a conflict with a friend as teenagers.


The researchers found that toddlers who were well treated by their mother and were best resolve conflicts adolescents tend to be committed in adult relationships.


People who stick, however, may be successful alone step taking a relationship together, researchers will be added.


Those who had similar commitment feelings - if these feelings were strong or weak - are more likely to stay together in the long term than the two persons whose level of commitment does not fit.


The study is published in the June issue of psychological Science.


In the study, couples were invited to tell how they tried to resolve a major conflict in their relationship and what they agreed for the most part. The researchers assessed their levels of hostility and feelings of despair on the relationship, and how couples tried to appease the other.


The study found that couples with different levels of commitment were the antagonists. When combined with a weak link, a strong link is losers and become the underdog with less influence. On the reverse, two weak links in a relationship can tolerate everything also low expectations.


The researchers concluded learn them that study findings open a window on the human understanding of how people to love. "Like children, you learn how to manage your own needs and those of the people you care about," said Mr. Minda writing of St. Olaf College in a press release from the Association for psychological Science. "You will learn: can I come forward with a problem." What can I expect from the other person? "And how can I do this so that everyone wins"?

Skin Cancer foes declared may 27 "Don't fry day"

on Friday, the beginning of the end of week Memorial Day, is also "Don ' T fry day," once for skin safety experts remind Americans about the dangers of overexposure to the Sun.


Melanoma, the potentially deadly form of skin cancer is the most common cancer in young adults in the late twenties, according to the U.S. Environmental Protection Agency (EPA) and the National Council for the prevention of Skin Cancerwho have joined forces to offer advice to save lives on the caution in the Sun. The main cause of skin cancer: overexposure to harmful ultraviolet (UV).


"Many people still don't realize that exposure to the Sun without protection can lead to cancer of the skin and other health problems," said Gina McCarthy, agency Administrator assistant for the EPA Office of Air and radiation, in a press release. "Simple steps, such as using a sunscreen, wear sunglasses or a hat, can protect us and our families, while still enjoying the outdoors."


Skin cancer, the most common type of cancer in the United States, affects more than 2 million U.S. dollars - every year more breast cancer, prostate, lung and colon combined, said the EPA. Every hour, an American dies of cancer of the skin, the Agency noted.


Although the UV rays are dangerous year round, the risks are greatest in the summer months when people spend more time outdoors, McCarthy said.


To limit exposure to harmful UV rays, expert proposes to you:

Cover you. One of the most effective ways to reduce the exposure to the harmful rays of the Sun is to wear a shirt, hat and sunglasses and Sunscreen SPF 15 +. Find a shady place. It is best to stay out of direct light from the Sun during peak hours, from 10 h to 16 h being aware of the UV index. Get involved in outdoor activities, check the UV index to identify the time more risky for overexposure to the Sun.

Combo of Paxil, Pravachol may raise the sugar in the blood (HealthDay)

 taken in combination, two drugs commonly prescribed antidepressant Paxil and the cholesterol-lowering Pravachol drugs seem increases significantly the blood glucose, a new study concludes.


The increase is more apparent - and for - in the diabetic whose blood sugar is already too high, the researchers noted.


"This interaction may affect up to 1 million Americans who would be on these two drugs and who get a bump in their blood glucose may be unnecessary," said researcher principal Dr. Russ Altman, Professor of biological, genetic engineering and medicine at Stanford University.


It is possible that the blood sugar spike triggered a diagnosis of diabetes type 2 patients, Altman said, "and we could avoid this diagnosis if they had not been on these drugs", he said. "This is speculative, but it is possible."


No single drug raises sugar in the blood and the researchers said they cannot yet explain the effect of the combination. Also, combinations of other antidepressants and cholesterol not stimulate glucose levels. "This is not what we would call a"class"effect", Altman explained.


Paxil (paroxetine) is in a class of drugs known as inhibitors of the reuptake of serotonin (SSRIS) and Pravachol (Pravastatin) belongs to a group of drugs called statins. "We looked at all the other pairs of SSRIS and Statins and there were a couple who has shown a small bump in glucose, but there is nothing to do with the humpback seen Paxil and Pravachol," Altman said.


For the study, published online may 25 in clinical and therapeutic Pharmacology, researchers have used a technique called data mining, analysis of large databases in the hope of finding information which, although not immediately obviousis gleaned by combining the data in a new way.


In this case, team Altman used the data from the U.S. Food and Drug Administration Adverse Event Reporting System, more data from the universities of Harvard, Stanford and Vanderbilt to identify the associations would not apparent doctors dealing with individual patients.


Using this method, researchers have identified 135 non-diabetic patients taking both drugs whose blood sugar increased of 19 milligrams per deciliter after the start of treatment. They have also identified 104 diabetic whose blood sugar increased an average of 48 mg/dl while taking the two drugs.


With levels of sugar in the blood of 126 mg/dl or two tests are considered diabetic. Levels of 100 mg/dl to 125 mg/dl are considered prédiabétiques.


By extrapolating these results to the whole of the population of the United States, the Altman team believes that of 33 million people taking Paxil or Pravachol, 500 000 to 1 million hold together.


To verify whether their conclusions were simply associations which could be explained by other factors, researchers have experimented with drugs in mice.


The mice were exposed to two drugs after receiving a diet rich in fat, high calorie to pre-diabetic. No single drug has increased sugar in the blood, together they have increased sugar in the blood of about 128 mg/dl to 193 mg/dl, the researchers found.


"It was just like humans in our data base, said Altman." So, this seems to be a real biological effect. "This could give us an overview of the mechanisms of diabetes."


Altman warns that people taking this drug combination should not respond.


He has said "people on an antidepressant should not mess with because depression is a very serious illness". It would be reasonable to see a doctor and see if your blood glucose have been difficult to control, he said. He said "if it was, then I think the thing to change would be the Statin,".


Dr. Ronald b. Goldberg, Professor of medicine at the Institute for research of diabetes at the University of Miami Miller School of Medicine, said that it was "" an interesting conclusion and could be clinically important. ""


"People with diabetes have an increased risk of depression." they are all recommended to be on Statins, "said Goldberg. "Then, it can worsen glycemic control in diabetic people."

But Goldberg thinks that it is too early to change clinical practice based on this study only. "This must be confirmed in a clinical trial," he said.



Childhood treatments related to gastrointestinal problems (HealthDay)

 children who are treated successfully for cancer are more at risk of developing severe mild gastrointestinal problems on the road, a new study concludes.


Researchers at the University of California, San Francisco analyzed the self-reported gastrointestinal (GI) problems of 14,358 patients surviving at least five years after the treatment of cancers such as lymphoma, leukemia, tumors of the brain or bone tumours.


More than 40 per cent have experienced some type of problem of IM - including ulcers, the disease of the esophagus, indigestion, polyps, chronic diarrhea, colitis, gallstones and jaundice - in two decades of their treatment, researchers have discovered.


In addition, people with cancer at a later age and who had to undergo a more rigorous treatment (chemotherapy, radiotherapy, surgery) were more likely to experience problems IM long term, according to the study of the may issue of Gastroenterology.


About one in 500 young adults in the United States is a survivor of childhood cancer, the study authors noted in a press release UCSF.


"While doctors continue to learn more about pediatric cancer and its treatment long term consequences, it is essential that we provide care of comprehensive follow-up that adequately addresses the complications can meet the cancer survivors.""," study lead author Dr. Robert Goldsby, specialist of pediatric cancer hospital for children of Benioff UCSF and Director of the UCSF Cancer of childhood survivors program, said in the press release.


"These are serious issues that can have a real impact on the quality of life of the person," added Goldsby.

Commitment capacity can begin early childhood

the ability of men and women of power staying and a high level of commitment in their relationships back to their childhood and adolescence, a new study concludes.


78 Persons aged 20 or 21 and their heterosexual partners on their level of commitment to their relationship, the researchers asked.


Researchers have already given on participants when they were between the ages of 16 and 2, including how loving and attentive, their mothers were while they were for toddlers, and how they dealt with a conflict with a friend as teenagers.


The researchers found that toddlers who were well treated by their mother and were best resolve conflicts adolescents tend to be committed in adult relationships.


People who stick, however, may be successful alone step taking a relationship together, researchers will be added.


Those who had similar commitment feelings - if these feelings were strong or weak - are more likely to stay together in the long term than the two persons whose level of commitment does not fit.


The study is published in the June issue of psychological Science.


In the study, couples were invited to tell how they tried to resolve a major conflict in their relationship and what they agreed for the most part. The researchers assessed their levels of hostility and feelings of despair on the relationship, and how couples tried to appease the other.


The study found that couples with different levels of commitment were the antagonists. When combined with a weak link, a strong link is losers and become the underdog with less influence. On the reverse, two weak links in a relationship can tolerate everything also low expectations.


The researchers concluded learn them that study findings open a window on the human understanding of how people to love. "Like children, you learn how to manage your own needs and those of the people you care about," said Mr. Minda writing of St. Olaf College in a press release from the Association for psychological Science. "You will learn: can I come forward with a problem." What can I expect from the other person? "And how can I do this so that everyone wins"?

DERMA Sciences foot-wound drug shows promise (Reuters)

BANGALORE (Reuters) - Derma Sciences Inc. said foot ulcers in 85% of diabetic patients healed completely after treatment with its experimental drug at the end of a trial of 24 weeks, improve its chances of licensing of the drug with potential partners.

Shares of the company, which specializes in wound care products, jumped 25 percent to a peak more of three months from $11.65 in afternoon trade on Wednesday on the Nasdaq.

Data will help the company to the outlicensing of the rights of the ex-états-Unis of the drug, code-named DSC127, a potential partner, Chief Executive Edward Quilty said in an interview.

Rodman & Renshaw analyst Michael Higgins said: "I think, the data from 24 weeks increased the bargaining power of the Derma with potential collaborators.

Higgins, who has a "market" to outperform rating on the stock, said that more impressed with the drug's ability to heal injuries 13.5 week earlier than the placebo.

The DERMA Quilty, said: "we certainly do not have the kind of money necessary to complete this test (late stage).". We (says the) Investment Committee that we were looking at all options available to us to help finance the trial. ?

Other that DSC127, Derma outlicensing may raise up to 50 million dollars of market fairness in its existing shelf registration statement.

Quilty, said most of the potential partners wanted to watch 24 weeks data and comprehensive benefits data, which will be submitted to the U.S. Food and Drug Administration.

It is expected to associate the drug later this year or early next year.

Barry Wolfenson, Executive Vice President of global marketing & business development, said: "I think that the real activity on partnerships for this will begin this week that we announce the data and begin to assemble a package and reach potential partners around the world."

If approved, the Derma drug is in competition with Johnson & Johnson Regranex for treating deep ulcers neuropathic diabetic foot.

"We believe that our data is stronger than Regranex," said Wolfenson.

If approved, DSC127 was rake up to 500 million dollars in annual sales to the United States, he said.

DATA FROM 24 WEEKS

The company said 85 percent of patients having completed protocols for eligibility, or population by Protocol (PP), has shown complete cure at 24 weeks, compared to 52% in the placebo group.

In the intent to treat population, where all patients are included, 73 per cent showed complete cure at 24 weeks, compared to 46% in the placebo group.

DERMA Sciences was developed to test the drug in two of the forces of dose and placebo controlled arm.

The trial showed a statistically significant difference in healing of the PP population at 24 weeks.

DERMA Sciences plans to begin trials of late phase of the drug in the first half of 2012. (Reported by Anand Basu in Bangalore.) (Editing by Prem Udayabhanu, Maju Samuel)

Wednesday, May 25, 2011

Women with high insurance subject to stop cancer drugs

 women taking breast cancer drugs are more likely to skip days or abandon processing entirely if their coinsurance is high, American researchers have found.


There is nothing new that people will often take the medicine that prescribes their doctor, but for cancer drugs, the consequences could be disastrous, experts say.


"Here we are talking about a drug to save lives,", said Dr. Alfred Neugut of Columbia University Medical Center in New York, whose results appear in the Journal of Clinical Oncology.


"Drugs are that important, perhaps that we put in place mechanisms to provide the means to circumvent the insurance or franchises."


Some insurance companies already have programs in place to ensure lower insurance for certain drugs, Neugut said, but they do cover inhibitor of aromatase, the focus of the new study.


These drugs, including Arimidex (AstraZeneca), significantly reduce the risk of death in cancer survivors who have been through menopause.


Arimidex can now be purchased as a generic drug for only less than a dollar by the pill, drug cost more than $2,000 per year when the study has been completed.


Neugut and colleagues used data from claims of MedCo Health Solutions to find out what role co-insurance patients could play or not, they took drugs for the recommended five years.


More 8 000 women aged 50 to 65, 20 percent stopped the drug at the beginning if their coinsurance was less than $30.


However, if the payment was $90 or more, 23 percent dropped drugs in advance.


For older women, the gap was five almost percentage, which Neugut chalks less available income.


There are similar differences in the number of women who jumped at least 20 per cent of the days, and the gap remained the same after researchers have considered possible explanations such as income and other factors.


"If the co-insurance gets too high, it will prevent people from taking a drug they really need," said Neugut, adding that previous research has noted the same effect for orders as a whole.


With health reform, more people should be covered by Medicaid, which means that they will have lower co-insurance. Neugut said that it is unclear what effect which were, in view of the beneficiaries of Medicaid but have fewer resources first.


He said that the problem is more serious for medicines against cancer than for other drugs, because the former deals with a potential fatal disease.


In addition, cancer drugs have side effects, which may also discourage women from taking them.


In General, Neugut told Reuters Health, "less than 50 per cent of women actually complete the five years - and if you do not, you lose most or all of the benefit of therapy."

The Sun-damage EPA raises awareness on 'not Fry day'

According to a press release from the U.S. Environmental Protection Agency, Friday is "Don't Fry Day" and is encouraged by the EPA as a means to spread awareness about the dangers of exposure to the Sun and the damage that can cause skinincluding serious skin cancers like melanoma.

For Don't Fry day, EPA works in partnership with the National Council on Skin Cancer Prevention to spread the message on the importance of protecting their skin, especially around the persons Memorial Day weekend and summer beginswhich in more people will be visit outside for summer activities. The EPA and the National Council on Skin Cancer Prevention provide easy advice to persons who are to minimize the risk of sun damage easy.

The tips include wearing a Jersey, using a sunscreen of at least 15 SPF, wearing hats and sunglasses to protect your eyes and sensitive areas of your face and seek shade when possible. EPA is also encourage people who are planning for the outdoor activities to check their local UV index, which tells you when the Sun's UV rays are most intense.

Gina McCarthy, assistant administrator for Office of Air and radiation EPA made a statement on the importance of the Americans to protect themselves from the Sun: "many people still don't realize that exposure to the Sun without protection can lead to cancer of the skin and other health problems." Simple steps, such as using a sunscreen, wear sunglasses or a hat can protect us and our families, while still enjoying the outdoors. ?

In addition, EPA is encouraging people to visit their website of the Sunwise program, dedicated to the promotion of awareness of the protection against the Sun. The website offers additional tips and resources.

EPA is also joining the States which have more than the rate of new cases of melanoma. According to another EPA press release, the Sunwise program is soft to the Northwest of the Pacific, including Oregon, Washington and Idaho.

Dennis McLerran, regional administrator of EPA in Seattle, commented on the importance of awareness of sun damage in the Pacific Northwest: "here in the Northwest Pacific and Alaska, where it may be cloudy and rainy, it is important that we protect ourselves from harmful UV rays.". Oregon, of Washington, and Idaho, are among the top ten new diagnosis of melanoma, it is therefore very important that we practice sun-safe behaviors throughout the year, not only in the spring and summer. ?

Rachel Bogart provides a thorough analysis of local environmental issues current and new in Chicago. As a student of the suburbs of Chicago, seeking to obtain two degrees of science, applied his knowledge and his passion for the two subjects to gather more public awareness.

Cancer Patients benefit from full access to medical records

Cancer Patients who are given full access to their medical record feel a greater sense of satisfaction about their treatment, a new study finds.


French researchers also concluded that provide complete and accurate medical information built of trust between the patient and the physician.


Published online on May 23 in the journal Cancer, the study analyzed 295 patients recently diagnosed cancer Lymphoma, breast or colon cancer. All were treated by chemotherapy.


Patients received either "on request information", or organized medical file (OMR) - a Briefcase complete detailed information on their condition and treatment. These information included reports on all, surgery, radiology and pathology results, with the nurse stories and observations of treatment. With SEO, they received guides on medical terms and understand the material, as well as to help medical personnel to decipher the various documents.


Eighty Eighteen per cent of patients who offered an OMR has chosen to take.


Patients who have received on-demand information has been provided only information and medical records if they asked for them or their doctor offered.


Similar anxiety and quality of life scores levels have been reported in the two groups.


But patients with OMR were 1.68 times more likely to be satisfied with their medical information and were 1.86 times more likely to feel fully informed, the authors of the study noted.


And 70.4% of the patients who received an OMR has said that they would once more to receive, with 74.8% saying: they not regret their choice. In addition, the majority of these patients has been reported that SEO was not the source of any anxiety.


"Information is crucial to make decisions of treatment options, and for the patient and his family, to cope with the disease and its consequences," study author Dr. Gwenaelle Gravis, the Paoli-Calmettes Institute in Marseillesaid in a press release of the editor of the journal. "Full access to his medical file with the possibility to consult only if you want increased patient confidence in the physician and the medical team."

More Docs to primary care in a community equals healthier seniors

primary care physicians more a community, especially those that are actually practicing primary care, that community healthier seniors are, suggests a new study by Dartmouth.


These communities see less avoidable hospitalizations and a slightly lower rate of mortality among seniors, the researchers found.


"This reinforces something resisted the American family physicians [AAFP] Academy for a long time: that a competent doctor can maintain results," said AAFP President Dr. Roland Goertz, who had observed that some 100 different studies is today the identical or similar conclusions. "."


This study and others come in the context of a pool of shrinkage of primary care physicians. A study last month revealed that the percentage of medical students who want to go into medicine for primary health care has fallen sharply during the past two decades, from 57% in 1990 to 33 for one hundred and twenty years later.


In 1990, 57 per cent wanted to go into medicine primary care against 33 per cent in 2007, this previous study. Those who choose to practice general internal medicine in 2007 fell by 9% to 2%. And in 2008, the medical students only 264 U.S. chose residency training in internal medicine, primary health care, compared to 575 in 1999.


But having more physicians primary care is a cornerstone of most of the strategies to improve the quality of health care and reduce costs to the United States, the authors of the current study report. Their finding appears in the issue of the Journal of the American Medical Association on May 25.


These authors have watched doctor claims for Medicare recipients about 5 million of 65 years and older from files of the American Medical Association. Claims coding for medical specialty and the type of care provided, said the author of the study Chiang-Hua Chang, an instructor of research with the Center for Health Policy Research at the Dartmouth Institute for health and clinical practice in the LibanN.H policy.


Elderly people in the regions where the greatest number of primary care physicians were less avoidable hospitalizations and fewer deaths.


The differences were certainly small. For example, the recruits of Medicare living in areas where the most per capita primary care physicians had a lower rate of 6% of preventable hospitalizations.


But the authors also found that it is not enough just to receive training in primary health care. To be practical primary care as well, something that future studies should take into account, the doctors said Chang.


Many trained primary care physicians appear to be exercising in specialties like emergency medicine, or only inpatient care, she added.


"I think that this raises several important issues," said Dr. Lawrence c. Kleinman, Associate Professor of evidence and health policy at the Mount Sinai School of Medicine in New York. "We must ensure that there is adequate distribution of these physicians and primary care physicians."


"Right now, we tend to be paid when physicians of things, but we tend to value when doctors prevent things, which means manpower moves from primary health care for specialized care,", he added.


The shortage will leave?


"Not in the way in which we currently organize and fund care", said Kleinman. "Medical students react to their value and their market forces and currently the amount of the debt and the repayment of variances are trumping the values of the people and other preferences."

Ejaculation ampio drug shows promise

BANGALORE  - Ampio Pharmaceuticals Inc. announced its drug to treat ejaculation showed statistically significant results in a late trial in Europe.

The drug, called Zertane, is regarded as needed before sexual activity and is not necessary to be taken on a daily basis.


Ampio said "the analysis of the results of the trial has exceeded our expectations." The company expects that the results of this test will allow the file to European regulatory approval for the drug. In his statement today, the company did not plans to market Zertane to the United States.


The active ingredient in Zertane is hydrocloride tramadol, which has been used to relieve the pain since the mid-1990s. Ampio specializes in "repositioning" drugs, i.e. testing of already approved drugs to find treatments for new indications.


Ampio said in a statement that ejaculation is the most common male sexual dysfunction, including about 23% of all men aged 18 to 75 years.


Bond Teen overcomes the fear of the young girl heart transplantation

WASHINGTON - heart of Courtney Montgomery was not quickly, but furiously, 16 years old was denied when his doctors and his mother, a transplant.


Previous surgeries had not helped and the daughter of North Carolina did not believe that this scarier operation would be. It should be an another teen is growing with a new heart to change opinion.


"I was like,"no, I do not want this."." If I'm going to die, I die,'"Said Courtney." "Now, I look back, I realize that wasn't think about the way I would have been.


Teens can add a complex psychology in organ transplantation: even if they are minor, they need to be on board with a transplant because it is for them to take care of their new organ. Depression, anger and cramping normal teenagers - tug-of-war with parents, try to adapt - can intervene. It is not just a matter of having the registry, but they are motivated how to stick with treatment anti-rejection for years to come.


"Making go us through, in terms of our ability to weigh the factors of rational way, probably not mature until you're in your late 20s," explains Dr. Robert Jaquiss, Chief of Pediatric Cardiac Surgery at Duke University Medical Centerwhere Courtney finally was transplanted. "It brought a huge level of complexity to care for these children."


Then there is the sense of isolation. Adolescents much less that older adults undergo organ transplants, making it unlikely that a young person has never seen the speed at which their peers can bounce.


Between 700 and 800 adolescents aged 11 to 17 years have some type of organ transplant each year. This almost 40 percent of Pediatric transplantation annual approximately 2 000. Teens are probably better than any other child or adult - age - the first year after surgery. But long-term, adolescents to make a little more evil that younger children, and the reason is biological, said Jaquiss. It is that teenagers and young adults tend to begin to slip on all required follow-up care.


A study found up to 40% of adolescents liver recipients possibly missing doses of drug or health. It can be normal development as teenagers start sleeping late and simply forget the dose of the morning, or sometimes the rebellion. There are side effects of medicines which said Jaquiss can be particularly troubling for this age group concerned of their image: weight gain, acne, and unwanted hair growth.


And research with the beneficiaries of heart was found at children's Hospital of Pittsburgh, chronological age is not linked to "medical maturity." For example, young patients who had difficulty accepting a transplant as normal and which avoids family discussion of problems, were less likely to consider carefully.


Mother of Courtney, Michelle Mescall, said that, when the Medical Centre has informed that her daughter should accept to go on the transplant waiting list, "I said, ' well it is a minor, what do you mean?" I'll take this decision. "I have just floor was now his decision. ?


Legally, the hospital could proceeded to OK the mother. But clinical social worker Shani Foy-Watson said that if this happened, the resentment of Courtney could torpedoed his healing, setting up these kinds of problems with follow-up care.


Foy-Watson, said it is not unusual for children living with a serious illness for years to have difficult to imagine the normality - at the same age when it is normal to seek more independent of their terrified parents.


Courtney, of Asheville, N.C., has been diagnosed at the age of 8 with hypertrophic cardiomyopathy, a heart thickened and hard at the pump which is the main cause of death in young athletes. His mother tried to avoid warnings from the death of physicians, but says that Courtney became anxious and depressed from the start.


She had an implanted defibrillator and cardiac surgery more later that offered only temporary relief, fueling the resentment of medical choice of his mother. Courtney had finally to give up his beloved flap, and last year needed home-school.


As a few weeks past with Courtney still withstand a transplant, the social worker tried a new tack: a 17-year old football player received a new heart at Duke a few months earlier by the same condition and was already back to school in Raleigh. He would meet with Courtney?


It was a bet. Nobody said Josh Winstead, now 18, the reason for the meeting, and they could not beat it. But they have fact, and Courtney immediately changed his mind.


"I suppose do me what I do, as a child, contributed to most," said Winstead, who took of Courtney to his prom a week before her surgery. "It was more just showing his normal how is my life.".


You will hear all the advice of friends and physicians, Courtney, said, "but he is not hit home as when Josh told me," I have the same scars that you do and is how he felt and how I feel now."" ?

She received her new heart last month. She is recovering well and exercising in the hope of getting back the pom team.

His mother helping Courtney learn to manage a huge 33 pills a day and is proud of the way in which his daughter joined: "I am just deal with how to let go and let him fly, but also be the parent of a child of 16 years".




Nations United met off the coast of destroy the last virus of smallpox

Geneva - health everywhere in the world, the Ministers agreed Tuesday to put off setting a deadline to destroy the last known stocks of virus of smallpox for three more years, rejecting a U.S. plan which called for a period of five years.

After two days of heated debate, the world the 193-nation Health Assembly agreed by consensus to a compromise that calls for a further review in 2014.

The United States had proposed an extension of five years to destroy the stocks American and Russian, arguing that other necessary research and stocks could help prevent one of the deadliest diseases in the world being used as a biological weapon.

But other Ministers in the decision-making Assembly of the World Health Organization said they saw little reason to conserve stocks and objected to the delay in their destruction.

Dr. Nils Daulaire, head of the U.S. Office of Global Health Affairs and the American delegate leader in the Assembly, has expressed some disappointment but said that the compromise was satisfactory.

"Three years is a reasonable period of time of the next revision", he told journalists. "It is clear that during this period of time, we anticipate there will be significant progress in research on antivirals and vaccines and diagnosis."

The Assembly declared smallpox officially eradicated in 1980, and the United Nations health agency has been discussed, whether to destroy the virus since 1986.

Then in 2007, the Assembly asked who is Director-General to oversee a thorough review of the situation so that the 2011 Assembly can agree on the destroy the last known stocks.

WHO officials said in a statement that the Assembly "strongly reaffirmed the decision of previous assemblies that remaining stocks of smallpox (variola) virus" should be destroyed in critical research based on the virus have been completed. ""

But the Assembly will once again faced with a decision over just when that up to three years from now.

The Assembly, as the General Assembly of the United Nations, is a global forum whose decisions are not legally binding, but moral weight. Therefore even if the Assembly has finally fixed a date for the destruction of stocks, it cannot force the United States and the Russia to comply.

Death of Joplin tornado up to 122, eighth more deadly on record (Reuters)

JOPLIN, Mo (Reuters) - a tornado of monster which ripped through the small town of Missouri southwest of Joplin Sunday killed at least 122 people and wounded about 750. authorities, said Tuesday

The number of dead revised 118 deaths made earlier Tuesday and makes it the giant tornado the eighth deadliest in the history of the United States, according to officials speaking at a press conference of.

The authorities also said that Joplin tornado has been upgraded to an EF-5, or the best possible rating on the enhanced Fujita of the power of the Tornado and the intensity scale. Joplin tornado had previously been assessed as an EF-4.

EF-5 tornado are rare in the United States, but already this year there were at least four - two in Mississippi, Alabama last month and Joplin. They are so destructive that experts have said that they can transform a House into an air missile. During the Joplin tornado winds were estimated at up to 200 miles per hour.

The tornado damaged Joplin a approximately 8 000 structures in the town of about 50,000, said authorities.

(Megan Gates reports;) Written by Greg McCune. (Editing by Jerry Norton)

Regular Brisk walking can protect patients with Cancer of the Prostate

Prostate cancer Patients who take great walks on a regular basis succeeds better than those who think the contrary, a new study suggests.


They not only reduce their risk of disease progression, they lower their chances of dying of the disease, researchers reported.


The conclusion is based on previous research in the same group of scientists who had indicated that "vigorous physical activity" reduces the risk of dying from prostate cancer.


"Men who participate in walking fast, defined as three miles per hour or faster, after clinically localized prostate cancer diagnosis had a reduction of the risk of progression of prostate cancer than men who walked to an easy pace less than two miles per hour"study author Erin said"" L. Richman, research associate in the Department of epidemiology and biostatistics at the University of California, San Francisco.


"Men who engaged in three hours per week or more brisk walking has had the greatest advantage", Richman added, "with a lower risk of 57% of the progression of the disease compared to men having come less than three hours per week at an easy pace." These results were independent clinical prognostic factors, dietary factors and factors of life such as obesity and smoking. ?


Report of the Richman appears in number 1 June of Cancer Research.


The authors of the study noted that about 2.2 million men are now struggling with a diagnosis of prostate cancer in the United States, and the disease is the second leading cause of cancer death in American men. In 2010, approximately 217,000 new cases were diagnosed.


To explore how lifestyle can influence the progression of the disease after a diagnosis, the study team focused on 1,455 patients with prostate cancer who were enrolled in one of the 40 Clinical Urology in 2004 and 2005.


At the time where the study launched, all men had localized cancer, which means that their disease had not yet spread beyond the prostate.


All the men completed a survey to assess their physical activity routines. Richman notes that most of the men had initially suffered "cure," including the radical treatment of prostactectomy or radiation.


The researchers found that walking represents approximately half of all physical activity exercised by patients, and that those that have been observed walking in so-called "deep" way tended to be younger and more appropriate than those who walked more slowly. Brisk walkers were also less likely to smoke.


By stacking patterns of exercise against signs of telltale of progression of the disease (such as the PSA levels, the spread of the disease or death), the research team found that patients who walked quickly for a minimum of three hours per week had a rate of progression of the disease (57 per cent below) significantly lesser than those who walked at an easy pace for less than three hours per week.


In fact, the pace of the March appeared to be more important than the amount of time spent walking. Walk at an easy pace conferred no advantage of protection against the progression of prostate cancer.


The team of the informed Richman that additional research is needed to confirm the results. She also suggested that other types of exercise may also be useful.


Mr. Lionel l. Banez, Assistant Professor in the division of Urologic Surgery, in the Department of surgery at Duke University Medical Center has agreed that further research might find that other forms of exercise provide similar protection.


"It's very reasonable to extrapolate these findings to include other forms of physical activity", he noted. "Our own previous study show that moderate exercise which included various forms of physical activity, has been associated with less aggressive prostate cancer risk in veterans."

Simply eating less fat may reduce the risk of diabetes

weight loss cannot be held to reduce the risk of a person for diabetes, a new study argues.


Rather, the study concluded, small dietary changes can make a big difference of risk, even without weight loss and for Blacks particularly.


For the study, published online may 18 in the American Journal of Clinical Nutrition, researchers have developed 69 obese people at risk for diabetes diet for eight weeks with only small reductions for their intake of carbohydrates to fat. Low-fat group consume a diet composed of 27% of fatty carbohydrates and 55%. Group feeding low carbohydrate was 39 per cent fat and 43% of carbohydrates.


"Eight weeks, the Group on the diet low fat had significantly higher insulin secretion and glucose tolerance better and tend to be higher insulin sensitivity," lead author of the study, Barbara Gowera Professor of nutritional sciences at the University of Alabama at Birmingham, said in a press release from the University. The findings have been described as more strong among black participants.


"These improvements indicate a decrease in the risk for diabetes," said Gower.


Surprisingly, she added, participants in the study were at low risk for the disease regardless of whether if they have lost any weight.


"People find it hard to lose weight," said Gower. "" "". What is important about our study is that the results suggest that attention to the quality of the diet, not the quantity, can make a difference in the risk of diabetes type 2. ?


Limiting the daily fat intake to about 27% of the diet of the person can reduce the risk of diabetes in the long term, a study found.


Researchers noted that the necessary dietary changes are minimal and therefore easy to manage.


"Diets used in this study were actually quite moderate," Laura Lee Gorée, a dietitian at the University and a co-author of the study, said in the press release. "People at risk for diabetes could easily adopt the diet low fat, we have used.".

Too many children getting antibiotics for asthma

while the guidelines recommend antibiotics for asthma, almost a million children with respiratory condition is prescribed drugs each year at the United States, a new study concludes.


"We are trying to reduce unnecessary antibiotics prescriptions, and suggests that as pediatricians, we are prescribing them too often, said researcher principal Dr. Ian M. Paul, Associate Professor of Pediatrics at the Faculty of Medicine of the University of Pennsylvania, Hershey's State.".


Why doctors prescribe antibiotics for asthma is not clear, Paul said. One of the reasons could be that physicians in treatment of severe asthma attack "feel the need to cover all their bases in also prescribing antibiotics", he suggested.


Sometimes parents can ask doctors to give their child antibiotics, but it does not appear to be a big factor, Paul noted. "There are probably some in clinical practice, but I do not think that happens all that often - certainly not in one in every six visits for asthma," he said.


"The encouraging conclusion was, when asthma education delivered during the visit, antibiotics were less likely to be prescribed", he added. When asthma education was not part of the visit, 19% of the time antibiotics were prescribed, compared to 11% when the teaching of asthma has been given.


"This suggests that we can raise families and patients and explain the causes of asthma and, hopefully, reduce prescribe them unnecessary antibiotic", said Paul.


The dangers of over-prescribing antibiotics are that it encourages the development of antibiotic-resistant bacteria and there are side effects to drugs themselves, Paul said.


The report was published in the online edition may 23 of Pediatrics.


The study, the team used Paul data from the National ambulatory medical and hospital care surveys Ambulatory Medical Care survey to see the rate of antibiotics prescribed for children between 1998 and 2007.


During this period, there were a few 60.4 million visits of medical care for children with asthma for which no prescription of antibiotics was justified. However, antibiotics were prescribed 16 percent of the time, researchers have discovered.


Primary care physicians were more likely to prescribe antibiotics, while that emergency physicians are less likely to prescribe them, said Paul.


Other factors that are linked to increased antibiotic prescription included corticosteroids and treated in the winter, the researchers noted.


However, when visits to primary care doctors included asthma, education, the antibiotic prescription rate has declined, Paul said.


In a second study in the same journal, Belgian researchers, led by Dr. Kris De Boeck, the Department of pediatric pulmonology and infectious diseases at University Hospital of Leuven, are like overprescription of antibiotics for asthmatic children.


These researchers found children treated with asthma drugs were 1.9 times more likely to also obtain a prescription for antibiotics, compared to children not treated with drugs against asthma.


In fact, 35.6% of children who have been prescribed drugs against asthma was also prescribed antibiotics, the researchers found.


"This finding highlights the need for education opportunities inform clinicians that this co-prescription should be limited," the authors concluded.


Commenting on the two studies, Dr. Paul Krogstad, Professor of pediatric infectious diseases at the University of California, Los Angeles and co-author of an editorial in the magazine that accompanies it, said that "these articles indicate that antibiotics and anti-asthmatic were very commonly prescribed two tandem here and Belgiquequi is in conflict with national and international recommendations that emphasize that the" antibiotics have no systematic use in the care of asthmatics. ?

Antibiotic overuse confuses the patient and the family, said Krogstad. "They do not understand the true nature of asthma as an inflammatory, not an infectious disease,"he explained.""

In addition, over-prescribing antibiotics leads to personal risk and society, said Krogstad.

"Personal risks include allergic reactions, side effects, drug interactions and costs." Societal costs include the costs associated with the medication and the choice of drug-resistant bacteria. Antibiotic overuse is reduced, but this remains an area where improvement is badly needed, "he says.