Researchers analyzed blood samples 12,090 between 1974 and 1986 Swedish men, whereas they were ages 44 to 50, samples of nearly 5,000 men, six years later, when they were aged 51 to 55 and samples of 1,167 men who were 60.
The men with PSA levels below the median, whereas they were 44-50 had a very low risk of death by cancer of the prostate or metastasis in 15 years. At the age of 60 years, these men with PSA levels below the median, the risk of prostate cancer had significantly decreased to 0.5%.
Although the current American Cancer Society guidelines suggest all but men at high risk should discuss screening with their doctor at the age of 50 years, the study authors say that their results indicate earlier tests could reduce unnecessary testing later.
The results indicate that more than half of men may waive regular PSA Test after this period and were just three tests PSA in their lives, with the first aged 44 to 50, the second between 51 and 55 years, and - if their PSA levels still low is - the third and last 60 years, said researchers at Memorial Sloan - Kettering Cancer Center in New York.
However, men with higher levels of PSA between the ages of 44 and 50 are high aggressive prostate cancer risk and should continue to undergo screening and APS as necessary, researchers have added.
The study to be presented to journalists today 18 may at the annual meeting of the American Society of Clinical Oncology.
"This research helps us to distinguish between men who can benefit from regular PSA for cancer of the prostate and the men who cannot be screening need not so often," lead author Dr. Hans Liljaa clinical chemist with appointments in the departments of medicine, laboratoireChirurgie and medicine, said in a press release of the Memorial Sloan-Kettering.
"Instead of testing all men efforts every year or every two years, screening and surveillance can concentrate on the early detection of cancer of the prostate in men who are considered at high risk of dying from the disease.".
PSA testing is recommended for the early detection of prostate cancer, but is associated with a high rate of over-diagnosis and excessive treatment, which is a concern because the treatment of cancer of the prostate can lead to erectile and urinary problems debilitating.
Because the study is presented at a medical meeting, its results should be considered preliminary until published in a refereed journal.
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